Lake Malawi/Niassa/Nyasa is the third deepest freshwater lake in the world. The basin is densely populated and has a high prevalence of water borne diseases. The lakes is home to 800 to 1000 fish species, making it the most fish species-rich lank in the world. The lake employs 56,000 fishers who harvest more than 100,000 tons of fish per year. Overall, the fishery supports the livelihoods of more than 1.6 million people. Major threats to the lake include overuse, invasive species, habitat degradation and deforestation, pollution and climate change.

Adaptive management is an ongoing natural resources management process of planning, doing, assessing, learning and adapting, while also applying what was learned to the next iteration of the natural resources management process. Adaptive management facilitates developing and refining a conservation strategy, making efficient management decisions and using research and monitoring to assess accomplishments and inform future iterations of the conservation strategy.

In May 2017, the African Great Lakes Conference: Conservation and Development in a Changing Climate was held in Entebbe, Uganda. This conference sought to increase coordination, strengthen capacity, inform policy with science, and promote basin-scale ecosystem management in the region. Because all of the African Great Lakes cross borders, the benefits they offer and the challenges they face are best managed at a basin-wide level.

The UNDP-UNEP Poverty Environment Initiative worked with the Government of Malawi to create revised policies for fisheries and forestry in order to produce better management of resources and encourage sustainable livelihoods. The project encouraged the government to engage stakeholders from various community groups in drafting the policies, which allowed local community leaders to provide a voice and offer their unique insights on how the policies should be shaped.